Parasitic Infection (Microsporidiosis Encephalitozoonosis) in Dogs

Encephalitozoonosis is an infection caused by the protozoal parasite, Encephalitozoon cuniculi. Protozoa are one-cell organisms that infect various cells or tissues of the body and behave as tiny parasites. Infection with E. cuniculi generally affects some combination of the kidneys, brain, heart, and lungs. This disease is also commonly called microsporidiosis, as the E. cuniculi is a parasite belonging to the species of microsporidia.

This relatively rare condition is transmitted through oronasal (mouth & nose route) when a dog licks or sniffs the spore-infected urine of the infected animals. Puppies are more prone to this condition due to their under developed immune systems. 

This condition is zoonotic which means it can transmit from animals to humans. Taking necessary precautions and sanitizing the environment are important steps to avoid this disease.


Neonatal infection (appears around three weeks of age)

Stunted growth

Poor hair coat, small size

Failure to thrive

Advances to kidney failure

Neurological complications



Brain abnormalities

Aggressive behavior



Progress to kidney failure

Leave a Comment