Skin Reactions to Drugs in Dogs

Cutaneous drug eruptions in dogs refer to adverse side effects caused by certain drugs, which affect the dog's skin. The term covers a spectrum of diseases and clinical signs which can vary markedly in clinical appearance and pathophysiology – the functional change that accompanies the disease. 

Cutaneous drug eruptions can often be characterized by blisters, or small bubbles on dog’s skin filled with fluid or pus.  Rash, or reddened, itchy skin, severe scratching and self-licking are also some common symptoms assoicated with cutageous drug eruptions.

Some other common symptoms may include:

Itchiness, scratching excessively

Flat, small red patches and raised bumps

Exfoliative erythroderma, a condition where at least 50 percent of the skin's body surface area turns bright red and scaly



Allergy symptoms

Skin redness and swelling

Patches of darker skin or plaques (round patches) that expand and may clear in the center, producing a bull’s-eye appearance

Blistering skin due to drug-induced pemphigus/pemphigoid (a rare autoimmune disorder of the skin)

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